In a report at the 240th National Meeting of the American Chemical Society on August 26, the team of stalwart frog-fanciers described enlisting colleagues worldwide to ship secretions from hundreds of promising frog skins to their laboratory in the United Arab Emirates. Using that amphibious treasure trove, they identified more than 100 antibiotic substances in the skins of different frog species from around the world. One even fights "Iraqibacter," the bacterium responsible for drug-resistant infections in wounded soldiers returning from Iraq.
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One substance isolated from the skin secretions of the Foothill Yellow-legged Frog -- a species once common in California and Oregon but now facing extinction -- shows promise for killing methicillin-resistant Staphylococcus aureus (MRSA) bacteria. MRSA is a "superbug," infamous for causing deadly outbreaks of infection among hospitalized patients. Now it is occurring in settings outside hospitals, including schools, nursing homes, and day care centers.
The skin of the mink frog, likewise, contains secretions that show promise for fighting "Iraqibacter," caused by multidrug-resistant Acinetobacter baumanni.